Gastric cancer - Chronic
Definition
A malignancy that forms in the lining of stomach (most commonly adenocarcinoma) with a characteristically insidious onset and poor prognosis
Preoperative evaluation and staging of gastric cancer
* Complete blood count
* Platelet count
* Basic metabolic panel
* Plain chest X-ray
* Positron emission tomography
* Pelvic ultrasound
* Esophagogastroduodenoscopy
Carcinoma of stomach
* CT of abdomen
* Endoscopic ultrasound of upper gastrointestinal tract
Medical History
* Helicobacter pylori gastrointestinal tract infection
* Gastritis, chronic
* Pernicious anemia
* Dietary finding
* Intestinal metaplasia of gastric mucosa
* Smoking
* Genetic predisposition
* Family history of Gastric cancer
* Distal subtotal gastrectomy
Findings
* Indigestion - Chronic
* Abnormal weight loss
* Nausea
* Abdominal pain
* Loss of appetite
* Early satiety
* Heartburn
* Dysphagia - Chronic
* Melena
* Vomiting
* Jaundice
* Abdominal mass
* Ascites
Tests
Suspected or known gastric carcinoma
* Esophagogastroduodenoscopy: Esophagogastroduodenoscopy (EGD) is the test of choice for detecting gastric cancer by allowing for direct visualization and biopsy of suspicious lesions .
Detection of gastric carcinoma .
* Endoscopic biopsy
Differential Diagnosis
* Indigestion - Chronic
* Dysphagia - Chronic
* Gastric ulcer
* Gastritis, acute
* Atrophic gastritis
* Gastric polyposis
* Barrett's esophagus
* Tuberculosis of stomach
Treatment
Drug Therapy
As an adjuvant to prevent recurrence following resection of gastric cancer
FLUOROURACIL
Metastatic disease from gastric cancer
FLUOROURACIL
Procedural Therapy
Gastric cancer
* Gastrectomy: Gastrectomy with or without lymph node dissection is the primary treatment for gastric cancer. The procedure employed is dependent on the stage of cancer .
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